Advanced Prostate Cancer

Comprehensive Treatment and Support at UPNT
A diagnosis of advanced prostate cancer can feel overwhelming. Understanding your options and having the right care team by your side can make a significant difference.
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At Urology Partners of North Texas (UPNT), we provide expert care and personalized treatment plans for patients with advanced prostate cancer. Our radiation oncologists specialize in the latest technologies, working closely with medical oncologists to ensure seamless, collaborative care.

What is Advanced Prostate Cancer?

Advanced prostate cancer is prostate cancer that has spread beyond the prostate gland. This can include nearby tissues (known as locally advanced prostate cancer) or more distant parts of the body, such as the bones, lymph nodes, or other organs (metastatic prostate cancer).

Types of Advanced Prostate Cancer

Current Treatment Strategies for Advanced Prostate Cancer

Treatment for advanced prostate cancer has evolved significantly in recent years. Today, combination therapies are recommended to slow disease progression and improve survival.

1. Hormone Therapy (Androgen Deprivation Therapy - ADT)

Hormone therapy is the backbone of treatment for advanced prostate cancer. It works by lowering testosterone, the hormone that fuels prostate cancer growth.

Options for hormone therapy include both injectable and oral medications:

Benefits of Oral ADT (Relugolix)

2. Combining ADT with Androgen Receptor Inhibitors (ARIs)

Recent studies show that combining ADT with an androgen receptor inhibitor (ARI) improves outcomes and delays disease progression. This combination therapy is recommended early for patients with hormone-sensitive prostate cancer, even before the cancer becomes resistant to hormone therapy.

Common ARI Combinations:

3. Radiation Therapy

Radiation therapy plays a key role in managing advanced prostate cancer, especially for locally advanced disease or to relieve pain from bone metastases.

UPNT’s radiation oncologists use advanced techniques such as Stereotactic Body Radiation Therapy (SBRT), which delivers highly precise doses of radiation with minimal damage to surrounding tissues.

4. Chemotherapy (When Needed)

Chemotherapy is recommended for cancers that are no longer responding to hormone therapy. UPNT works closely with medical oncologists to coordinate chemotherapy care.

Common Chemotherapy Drugs:

5. Clinical Trials and Emerging Therapies

UPNT is proud to offer access to clinical trials, giving patients the opportunity to receive promising new treatments before they become widely available. Clinical trials may include immunotherapy, PARP inhibitors, or targeted therapies for patients with specific genetic mutations (e.g., BRCA mutations).

Participating in a clinical trial can provide cutting-edge care while helping to advance future treatments.

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How is Advanced Prostate Cancer Diagnosed?

Diagnosing advanced prostate cancer involves a combination of blood tests, imaging studies, and sometimes biopsies to determine how far the cancer has spread. One of the most exciting advancements in recent years is the PSMA PET scan, a powerful imaging tool that offers greater accuracy than traditional CT scans or bone scans.

What is a PSMA PET Scan?

PSMA (Prostate-Specific Membrane Antigen) PET imaging is a highly sensitive scan that detects prostate cancer cells throughout the body. It uses a small amount of a radioactive tracer that binds specifically to PSMA, a protein found on prostate cancer cells. This allows for highly accurate imaging of cancer spread.

At UPNT, we work closely with partners to offer patients access to the most advanced imaging technologies, including PSMA PET scans, ensuring an accurate diagnosis and well-informed treatment decisions.

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Managing Side Effects and Quality of Life

At UPNT, we focus on treating the whole person, not just the disease. Managing side effects and maintaining quality of life are integral parts of our care approach.

Common Side Effects of Treatment

Support Strategies

Frequently Asked Questions (FAQs)

1. Why combine ADT with androgen receptor inhibitors?

Combining ADT with ARIs improves survival and delays disease progression compared to ADT alone.

Radiation can help control localized cancer and reduce pain from bone metastases.
While a complete cure is rare, many treatments can control the disease for years and improve quality of life.
New therapies include advanced hormone therapies, targeted drugs, and immunotherapy through clinical trials.
Still have questions?

Conclusion: Trust UPNT for Advanced Prostate Cancer Care

At UPNT, we combine expertise in radiation oncology with a collaborative approach, working closely with leading medical oncologists to deliver the best care possible. Our commitment to personalized treatment plans, access to clinical trials, and innovative therapies ensures that patients receive the most up-to-date and effective care available.

If you or a loved one has been diagnosed with advanced prostate cancer, contact UPNT today to learn how we can help you navigate your journey.

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